Isabel Quirós-Gonzalez

I study the development of blood vessels (angiogenesis) during cancer progression using optoacoustic imaging and the effect of anti-angiogenic treatments on pro-angiogenic pathways such as hypoxia, inflammation and oxidative stress. Our final goal is to increase the current knowledge about resistance to anti-angiogenic therapy in breast cancer.

Brief CV

BSc MSc Biology, University of Oviedo, Spain (2000-2005)
PhD Biomedical Sciences, University of Oviedo, Spain (2006-2011)
Postdoc with Prof. Jorge Andia, Hospital Universitario Central de Asturias, Spain (2011-2012)
ERA-EDTA-EMBO Postdoc fellow at Wellcome Trust Sanger Institute, UK (2013-2014)
Postdoctoral Research Fellow with Dr Sarah Bohndiek, University of Cambridge, UK (2015-2018)

Next destination: Clarin Fellow, University of Ovideo, Spain

Publication Highlights

Optoacoustics delineates murine breast cancer models displaying angiogenesis and vascular mimicry

Published to Springer Nature

Quiros-Gonzalez I , Tomaszewski M, Aitken S, Ansel-Bollepalli L, McDuffus L, Gill M, Hacker L, Brunker J and Bohndiek S E (2018) Br J Cancer

Vitamin B12–dependent taurine synthesis regulates growth and bone mass.

Published to PubMed

Roman-Garcia P*, Quiros-Gonzalez I*, Mortram L*, Lieben L, Sharan K, Wangwiwatsin A, Tubio J M, Lewis K, Yu E Y, Helfrich M H, Guo X E, Santhanam B, Clare S, Vassiliou G S, Velagapudi V R, Dougan G and Yadav V K (2014) J Clin Invest 124(7):2988-3002.

MnSOD drives neuroendocrine differentiation, androgen-independence and cell survival in prostate cancer cells.

Published to PubMed

Quiros-Gonzalez I, Sainz RM, Hevia D and Mayo JC (2011) Free Radic Biol Med 50(4):525-36.