Joanna Brunker | Vision Lab

I propose to develop a toolbox of genetically expressed photoacoustic reporters enabling pre-clinical photoacoustic imaging of tumour hypoxia alongside blood oxygenation and glycolysis. Understanding the relationship of blood oxygenation (measurable endogenously) to tissue hypoxia and other biological processes including glycolysis (requiring exogenous markers) will improve cancer treatment outcomes. The reporters could also provide insights into the biology of many other diseases.

Brief CV

PhD in Medical Physics and Bioengineering, UCL (2010-2014)
EPSRC fellowship, UCL (2014-2016)
Postdoctoral research associate, Cambridge (2016-2017)
Cambridge-Wellcome fellowship, Cambridge (2017-2019)

Publication Highlights

Photoacoustic imaging using genetically encoded reporters: a review.

Published to PubMed

J. Brunker, J. Yao, J. Laufer and S. E. Bohndiek. (2017) J. Biomed. Opt. 22, 070901-1 – 070901-18.

Velocity measurements in whole blood using acoustic resolution photoacoustic Doppler.

Published to PubMed

J. Brunker and P. Beard. (2016) Biomed. Opt. Express 7, 2789–2806.

Pulsed photoacoustic Doppler flowmetry using time-domain cross-correlation: accuracy, resolution and scalability,

Published to PubMed

J. Brunker and P. Beard (2012) J. Acoust. Soc. Am. 132, 1780–1791.

Best conference attended so far:

TOPIM-TECH 2017, Crete