Full Publication List

2018

Bimodal reflectance and fluorescence multispectral endoscopy based on spectrally resolving detector arrays

Posted on , Published to PubMed

A S Luthman, D J Waterhouse, L Ansel-Bollepalli, J Yoon, G S D Gordon, J Joseph, M di Pietro, W Januszewicz and S E Bohndiek (2018) J Biomed Opt. 24(3):1-14

Reconstruction of optical vector-fields with applications in endoscopic imaging

Posted on , Published to PubMed

M Gataric, G S D Gordon, F Renna, A G C P Ramos, M P Alcolea and S E Bohndiek (2018) Epub ahead of print at IEEE Trans Med Imaging.

An active DNA-based nanoprobe for photoacoustic pH imaging.

Posted on , Published to PubMed

K N Baumann, A C Fux, J Joseph, S E Bohndiek and S Hernández-Ainsa (2018) Epub ahead of print at Chem Commun (Camb)

Raman micro-spectroscopy for accurate identification of primary human bronchial epithelial cells.

Posted on , Published to PubMed

J M Surmacki, B J Woodhams, A Haslehurst, B A J Ponder and S E Bohndiek (2018) Sci Rep 8(1):12604

Oxygen-enhanced and dynamic contrast-enhanced optoacoustic tomography provide surrogate biomarkers of tumour vascular function, hypoxia and necrosis.

Posted on , Published to PubMed

M. R. Tomaszewski, M Gehrung, J Joseph, I Quiros Gonzalez, J A Disselhorst and S E Bohndiek (2018) Epub ahead of print at Cancer Res.

Graphitic and oxidised high pressure high temperature (HPHT) nanodiamonds induce differential biological responses in breast cancer cell lines.

Posted on , Published to PubMed

B Woodhams, L Ansel-Bollepalli, j Surmacki, H Knowles, L Maggini, M de Volder, M Atatüre and S E Bohndiek. (2018) Epub ahead of print at Nanoscale.

Optoacoustic Imaging Detects Hormone-Related Physiological Changes of Breast Parenchyma.

Posted on , Published to PubMed

O Abeyakoon, S Morscher, N Dalhaus, S J Ford, I A Mendichovszky, R Manavaki, M Wallis, P Moyle, R Woitek, A Patterson, T Torheim, J Joseph, I Q Gonzalez, S E Bohndiek, F J Gilbert. (2018) Epub ahead of print at Ultraschall Med.

Smart-Dust-Nanorice for Enhancement of Endogenous Raman Signal, Contrast in Photoacoustic Imaging, and T2-Shortening in Magnetic Resonance Imaging.

Posted on , Published to PubMed

C Pohling, J L Campbell, T A Larson, D Van de Sompel, J Levi, M H Bachmann, S E Bohndiek, J V Jokerst and S S Gambhir. (2018) ePub ahead of print at Small.

Emerging optical methods for endoscopic surveillance of Barrett’s oesophagus.

Posted on , Published to PubMed

D J Waterhouse, C R M Fitzpatrick, M di Pietro and S E Bohndiek. (2018) Lancet Gastroenterol Hepatol. 3(5):349-362

Optoacoustics delineates murine breast cancer modelsdisplaying angiogenesis and vascular mimicry

Posted on , Published to PubMed

I Quiros-Gonzalez, M Tomaszewski, S Aitken, L Ansel-Bollepalli, L McDuffus, M Gill, L Hacker, J Brunker and S E Bohndiek (2018) ePub ahead of print at Br J Cancer

Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species.

Posted on , Published to PubMed

L M Needham, J Weber, J W B Fyfe, O M Kabia, D T Do, E Klimont, Y Zhang, M Rodrigues, C M Dobson, S Ghandi, S E Bohndiek, T N Snaddon, S F Lee. (2018) R Soc Open Sci. 5(2):171399

Processing methods for photoacoustic Doppler flowmetry with a clinical ultrasound scanner

Posted on , Published to PubMed

Thore M. Bücking; Pim J. van den Berg; Stavroula Balabani; Wiendelt Steenbergen; Paul C. Beard; Joanna Brunker

Detection of early neoplasia in Barrett’s esophagus using lectin-based near-infrared imaging: an ex vivo study on human tissue.

Posted on , Published to PubMed

A A Neves, M Di Pietro, M O'Donovan, D J Waterhouse, S E Bohndiek, K M Brindle and R C Fitzgerald. (2018) ePub ahead of print at Endoscopy .

2017

Distance dependent photoacoustics revealed through DNA nanostructures.

Posted on , Published to PubMed

J Joseph, K N Baumann, P Koehler, T J Zuehlsdorff, D J Cole, J Weber, S E Bohndiek and S Hernández-Ainsa. (2017) ePub ahead of print at Nanoscale.

Optoacoustic detection of early therapy-induced tumor cell death using a targeted imaging agent.

Posted on , Published to PubMed

B Xie, M R Tomaszewski, A Neves, S Ros, D Hu, S McGuire, S Mullins, D A Tice, R C A Sainson, S E Bohndiek, R W Wilkinson and K M Brindle. (2017) ePub ahead of print at Clin Cancer Res.

Current and Emerging Technologies for Probing Molecular Signatures of Traumatic Brain Injury.

Posted on , Published to PubMed

A Ercole, S Magnoni, G Vegliante, R Pastorelli, J Surmacki, S E Bohndiek and E R Zanier. (2017) Frontiers Neurology 8 (AUG) 450.

Photoacoustic imaging using genetically encoded reporters: a review.

Posted on , Published to PubMed

J Brunker, J J Yao, J Laufer and S E Bohndiek. (2017) J. Biomed. Opt. 22 (7) 070901.

Oxygen enhanced photoacoustic imaging reveals vascular dynamics in murine models of prostate cancer.

Posted on , Published to PubMed

M R Tomaszewski, I Quiros-Gonzalez, J O'Connor, O Abeyakoon, G Parker, K Williams, F Gilbert and S E Bohndiek (2017) Theranostics. 7 (11) 2900-2915.

Wide field fluorescence hyperspectral imaging (fHSI) for biomedical applications.

Posted on , Published to PubMed

A S N Luthman, S Dumitru, I Quiros-Gonzalez, J Joseph and S E Bohndiek. (2017) J. Biophotonics. 10 (6-7) 840-853.

Tolerancing the alignment of large core optical fibers, fiber bundles and light guides using a Fourier approach.

Posted on , Published to PubMed

T W Sawyer, R Petersberg and S E Bohndiek (2017) Appl Opt. 56 (12) 3303-3310.

Assessing oxidative stress in tumors by measuring the rate of hyperpolarized [1-13C]dehydroascorbic acid reduction using 13C magnetic resonance spectroscopy.

Posted on , Published to PubMed

K N Timm, D Hu, M Williams, A J Wright, M I Kettunen, B W Kennedy, T J Larkin, F Bulat, P Dzien, I Marco-Rius, S E Bohndiek and K M Brindle (2017) J Biol Chem. 292 (5) 1737-1748.

Imaging biomarker roadmap for cancer studies.

Posted on , Published to PubMed

J P B O’Connor, …, S E Bohndiek et al (2017) Nature Reviews Clin Onc. 14 (3) 169-186.

Evaluation of illumination system uniformity for wide-field biomedical hyperspectral imaging.

Posted on , Published to IoP

T W Sawyer, A S N Luthman and S E Bohndiek (2017). J Opt. 19 045301.

Evaluation of precision of optoacoustic tomography for preclinical imaging of living subjects.

Posted on , Published to PubMed

J Joseph, M R Tomaszewski, I Quiros Gonzalez, J Weber, J Brunker and S E Bohndiek. (2017) J Nucl Med. 58 807-814.

Label-free monitoring of tissue biochemistry following traumatic brain injury using Raman spectroscopy.

Posted on , Published to PubMed

J M Surmacki, L Bollepalli, F Pischiutta, E R Zanier, A Ercole and S E Bohndiek. (2017) Analyst. 142 132-139.

2016

Towards Quantitative Evaluation of Tissue Absorption Coefficients Using Light Fluence Correction in Optoacoustic Tomography

Posted on , Published to PubMed

F M Brochu, J Brunker, J Joseph, M R Tomaszewski, S Morscher and S E Bohndiek (2017) IEEE Trans Med Imag 36 (1) 332-331.

Design and validation of a near-infrared fluorescence endoscope for detection of early esophageal malignancy

Posted on , Published to PubMed

D J Waterhouse, J Joseph, A A Neves, M di Pietro, K M Brindle, R C Fitzgerald and S E Bohndiek (2016) J. Biomed. Opt. 21(8), 084001.

Contrast Agents for Molecular Photoacoustic Imaging

Posted on , Published to PubMed

J Weber, P C Beard and S E Bohndiek (2016) Nat Meth 13(8):639-50

2015

Single-pixel phase-corrected fiber bundle endomicroscopy with lensless focussing capability.

Posted on , Published to IEEExplore

G S D Gordon, J Joseph, S E Bohndiek and T D Wilkinson (2015) J Lightwave Technol. 33 16 3419-3425.

Photoacoustic tomography detects early vessel regression and normalization during ovarian tumor response to the anti-angiogenic therapy Trebananib.

Posted on , Published to PubMed

S E Bohndiek, Laura S Sasportas, Steve Machtaler, Jesse V Jokerst, Sharon Hori and Sanjiv S Gambhir (2015) J Nucl Med. Accepted.

2014

Active Pixel CMOS-Based Radiation Detectors

Posted on , Published to ScienceDirect

C Arvanitis and S E Bohndiek (2014) ‘Chapter 618: Active Pixel CMOS-Based Radiation Detectors’ in Comprehensive Biomedical Physics (Elsevier)

Analysis of image heterogeneity using 2D Minkowski functionals detects tumor responses to treatment.

Posted on , Published to PubMed

T Larkin, H Canuto, M Kettunen, T Booth, D Hu, A S Krishnan, S E Bohndiek, A A Neves, C McLachlan, M P Hobson and K M Brindle (2014) Magn Reson Med 71 (1) 402-410.

Quantitation of a spin polarization-induced nuclear Overhauser effect (SPINOE) between a hyperpolarized 13C-labeled cell metabolite and water protons.

Posted on , Published to PubMed

I Marco-Ruis, S E Bohndiek, M I Kettunen, T J Larkin, M Basharat, C Seeley and K M Brindle (2014) Contrast Media Mol Imaging 9 (2) 182-186.

Cellulose nanoparticles are a biodegradable photoacoustic contrast agent in living mice.

Posted on , Published to ScienceDirect

J V Jokerst, D Van de Sompel, S E Bohndiek, and S S Gambhir (2014) Photoacoustics. 2 3 119-127.

2013

Molecular imaging with gold nanoparticles combined with Surface Enhanced Raman Spectroscopy

Posted on , Published to FutureMedicine

S E Bohndiek and S S Gambhir (2013) Imaging Med 5 (1) 11-14.

Molecular photoacoustic imaging of follicular thyroid carcinoma.

Posted on , Published to PubMed

J Levi, S R Kothapalli, S E Bohndiek, J K Yoon, A Dragulescu-Andrasi, C Nielsen, A Tisma, S Bodapati, G Gowrishankar, X Yan, C T Chan, D Starcevic and S S Gambhir (2013) Clin Cancer Res 19 (6) 1-9.

Development and application of stable phantoms for the evaluation of photoacoustic imaging instruments.

Posted on , Published to PubMed

S E Bohndiek, S Bodapati, D Van De Sompel, S R Kothapalli and S S Gambhir (2013) PLoS One 8 (9) e75533.

A small animal Raman instrument for rapid, wide-area, spectroscopic imaging

Posted on , Published to PubMed

S E Bohndiek, A Wagadarikar, C L Zavaleta, D Van De Sompel, E Garai, J V Jokerst, S Yazdanfar and S S Gambhir (2013) Proc Natl Acad Sci USA 110 (30) 12408-12413

2012

Hyperpolarized 13C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization.

Posted on , Published to PubMed

S E Bohndiek, M I Kettunen, D Hu and K M Brindle (2012) Cancer Res 72 854-864.

Magnetic resonance imaging with hyperpolarized [1, 4-13C2] fumarate allows detection of early renal acute tubular necrosis.

Posted on , Published to PubMed

M R Clatworthy, M I Kettunen, D Hu, R J Mathews, T H Witney, B W C Kennedy, S E Bohndiek, F A Gallagher, L B Jarvis, K G C Smith and K M Brindle (2012) Proc Natl Acad Sci USA 109 (33) 13374-13379.

Improving image quality by accounting for changes in water temperature during a photoacoustic tomography scan.

Posted on , Published to PubMed

D Van de Sompel, L S Sasportas, A Dragulescu-Andrasi, S E Bohndiek and S S Gambhir (2012) PLoS ONE 7 (10) e45337.

2011

Tumor imaging using hyperpolarized 13C magnetic resonance spectroscopy.

Posted on , Published to PubMed

K M Brindle, S E Bohndiek, F A Gallagher and M I Kettunen (2011) Magn Reson Med 66 (2) 505-19.

Hyperpolarized 13C MRS and PET: complementary techniques for investigating tumor biochemistry in vivo.

Posted on , Published to PubMed

F A Gallagher, S E Bohndiek, M I Kettunen, D Y Lewis, D Soloviev and K M Brindle (2011) J Nucl Med 52 (9) 1333-1336.

Hyperpolarized [1-13C]-Ascorbic and Dehydroascorbic Acid: Vitamin C as a probe for imaging redox status in vivo

Posted on , Published to PubMed

S E Bohndiek, M I Kettunen, D Hu, B W C Kennedy, J Boren, F A Gallagher and K M Brindle (2011) J Am Chem Soc A 133 (30) 11795-11801.

2010

Magnetization Transfer Measurements of Exchange between Hyperpolarized [1-13C]-pyruvate and [1-13C]-lactate in a murine lymphoma.

Posted on , Published to PubMed

M I Kettunen, D Hu, T H Witney, R McLaughlin, F A Gallagher, S E Bohndiek, S E Day and K M Brindle (2010) Magn Reson Med 63 (4) 872-880.

Optical characterisation of a CMOS active pixel sensor using periodic noise reduction techniques.

Posted on , Published to ScienceDirect

A C Konstantinidis, A Olivo, P Munro, S E Bohndiek and R Speller (2010) Nucl Inst Meth A 620 (2-3) 549-556.

Characterisation of regional variations in a stitched CMOS active pixel sensor.

Posted on , Published to ScienceDirect

H M Zin, A C Konstantinidis, E J Harris, J F P Osmond, A Olivo, S E Bohndiek, A T Clark et al (2010) Nucl Inst Meth A 620 (2-3) 540-548.

Imaging and ‘omic’ methods in the molecular diagnosis of cancer.

Posted on , Published to PubMed

S E Bohndiek and K M Brindle (2010) Expert Rev Mol Diagn 10 (4) 417-434.

Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarized [1-13C]pyruvate and [1,4-13C2]fumarate

Posted on , Published to PubMed

T H Witney, M I Kettunen, D Hu, F A Gallagher, S E Bohndiek, R Napolitano and K M Brindle (2010) Br J Cancer 103 (9) 1400-1406.

Detecting tumor response to a vascular disrupting agent using 13C magnetic resonance spectroscopy and hyperpolarized [1-13C]pyruvate and [1,4-13C2]fumarate.

Posted on , Published to PubMed

S E Bohndiek, M I Kettunen, D Hu, T H Witney, B W C Kennedy, F A Gallagher and K M Brindle (2010) Mol Cancer Ther 9 (12) 3278 – 3288.

2009

Signal and noise transfer of a CMOS based active pixel flat panel imager coupled to structured CsI:Tl.

Posted on , Published to PubMed

C D Arvanitis, S E Bohndiek, J Blakesley, A Olivo and R D Speller (2009) Med Phys 36 116-126.

A CMOS Image Sensor with In-Pixel ADC, Timestamp and Sparse Readout.

Posted on , Published to IEEExplore

J P Crooks, S E Bohndiek, H XingLiang, B Ott, J Osmond, G Villani, A Clark, R Halsall, M et al (2009) IEEE Sensors 9 20-28.

A non-free-space propagation x-ray phase contrast imaging method sensitive to phase effects in two directions simultaneously.

Posted on , Published to AIP

A Olivo, S E Bohndiek, J Griffiths, A Konstantinidis and R D Speller (2009) Appl Phys Lett 94 044108.

An Active Pixel Sensor-based X-ray diffraction system for breast biopsy analysis.

Posted on , Published to PubMed

S E Bohndiek, G J Royle and R D Speller (2009) Phys Med Biol 54 3513-3527.

The Multidimensional Integrated Intelligent Imaging project (MI-3).

Posted on , Published to PubMed

N Allinson, T Anaxagoras, J Aveyard, C Arvanitis, R Bates, A Blue, S E Bohndiek, J Cabello et al (2009) Nucl Inst Meth A 604 196-198.

Characterization and testing of LAS: a prototype ‘Large Area Sensor’ with performance characteristics suitable for medical imaging applications. I

Posted on , Published to IEEExplore

S E Bohndiek, A Blue, J Cabello, A T Clark, N Guerrini, P M Evans, E J Harris, A Konstantinidis, et al (2009) EEE Trans Nucl Sci 56 (5) 2938-2946.

Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.

Posted on , Published to PubMed

F A Gallagher, M I Kettunen, D Hu, P R Jensen, R in't Zandt, M Karlsson, A Gisselsson,... S E Bohndiek, et al (2009) Proc Natl Acad Sci USA 106 (47) 19801-19806.

2008

A CMOS Active Pixel Sensor system for laboratory-based x-ray diffraction of biological tissue.

Posted on , Published to PubMed

S E Bohndiek, E J Cook, C D Arvanitis, A Olivo, G J Royle, A T Clark, M L Prydderch, R Turchetta and R D Speller (2008) Phys Med Biol 53 655-672.

Comparison of methods for estimating the conversion gain of CMOS Active Pixel Sensors.

Posted on , Published to IEEExplore

S E Bohndiek, A Blue, A T Clark, M L Prydderch, R Turchetta, G J Royle and R D Speller (2008) IEEE Sensors 10 1734-1744.

2007

Characterisation of Vanilla – A novel active pixel sensor for radiation detection.

Posted on , Published to ScienceDirect

A Blue, R Bates, A Laing, D Maneuski, V O’Shea, A Clark, S E Bohndiek et al (2007) Nucl Inst Meth A 591 287-290.

Correlation of energy dispersive diffraction signatures and microCT of small breast tissue samples with pathological analysis.

Posted on , Published to PubMed

J A Griffiths, G J Royle, A M Hanby, J A Horrocks, S E Bohndiek and R D Speller (2007) Phys Med Biol 52 6151-6164.

First evidence of phase-contrast imaging with laboratory sources and active pixel sensors.

Posted on , Published to ScienceDirect

A Olivo, C D Arvanitis, S E Bohndiek, A T Clark, M Prydderch, R Turchetta and R D Speller (2007) Nucl Inst Meth A 581 776-782.

Empirical electro-optical and x-ray performance evaluation of CMOS Active Pixel Sensors for low dose, high resolution x-ray medical imaging.

Posted on , Published to PubMed

C D Arvanitis, S E Bohndiek, G J Royle, A Blue, H X Liang, A Clark, M Prydderch, R Turchetta, R D Speller (2007) Med Phys 34 4612-4625.

Characterization studies of two novel Active Pixel Sensors.

Posted on , Published to SPIE

S E Bohndiek, C D Arvanitis, G J Royle, A T Clark, J P Crooks, M L Prydderch, R Turchetta, A Blue, V O’Shea and R D Speller (2007) Opt Eng 46 124003.