2022

Multispectral imaging of nailfold capillaries using LED illumination.

Posted on December 27th, 2022, Published to

M Taylor-Williams, S Mead, T W Sawyer, L Hacker, C Williams, M Berks, A Murrau and S E Bohndiek (2022) J Biomed Opt 27 (12) 126002.

Photoacoustic imaging radiomics in patient-derived xenografts: a study on feature sensitivity and model discrimination.

Posted on December 27th, 2022, Published to

L E Sanchez, E Brown, L Rundo, S Ursprung, E Sala, S E Bohndiek and I X Partarrieu (2022) Sci Rep 12 1.

Noninvasive hemoglobin sensing and imaging: optical tools for disease diagnosis.

Posted on November 27th, 2022, Published to

M Taylor-Williams, G Spicer, G Bale and S E Bohndiek (2022) J Biomed Opt. 27 (8) 080901.

An optoacoustic imaging feature set to characterize blood vessels surrounding benign and malignant breast lesions.

Posted on September 27th, 2022, Published to

O Abeyakoon, R Woitek, M G Wallis, P L Moyle, S Morscher, N Dalhaus, S J Ford, N C Burton, R Manavaki, I A Mendichovsky, J Joseph, I Quiros-Gonzalez, S E Bohndiek* and F J Gilbert* (2022) Photoacoustics 27 100383.

Criteria for the design of tissue-mimicking phantoms for the standardisation of biophotonic instrumentation.

Posted on September 27th, 2022, Published to

L Hacker, H Wabnitz, A Pifferi, B W Pogue, J Pfefer and S E Bohndiek (2022) Nat Biomed Eng. 6 541-558.

Quantification of vascular networks in photoacoustic mesoscopy.

Posted on May 27th, 2022, Published to

E L Brown, T L Lefebvre, P W Sweeney, B J Stolz, J Gröhl, L Hacker, Z Huang, D Couturier, H A Harrington, H M Byrne and S E Bohndiek (2022) Photoacoustics 26 100357.

SIMPA: An open source toolkit for simulation and processing for Photonics and Acoustics.

Posted on May 27th, 2022, Published to

J Gröhl#, K K Dreher#, M Schellenberg, T Rix, N Holzwarth, P Vieten, L Ayala, S E Bohndiek, A Seitel and L Maier-Hein (2022) J Biomed Opt. 27 (8) 083010.

Photoacoustic tomography indicates response and resistance to Bevacizumab in breast cancer mouse models.

Posted on April 27th, 2022, Published to

I Quiros-Gonzalez, M R Tomaszewski, M A Golinska, E Brown, L Ansel-Bollepalli, L Hacker D Couturier, R M Sainz and S E Bohndiek (2022) Cancer Res 82 (8) 1658-1668.

Evaluation of label-free confocal Raman micro-spectroscopy for monitoring oxidative stress in vitro in live human cancer cells.

Posted on April 27th, 2022, Published to

J Surmacki, I Quiros-Gonzalez and S E Bohndiek (2022) Antioxidants 11 (3) 573.

The IPASC data format: A consensus data format for photoacoustic imaging.

Posted on March 27th, 2022, Published to

J Gröhl#, L Hacker#, B T Cox, K K Dreher, S Morscher, A Rakotondrainibe, F Varray, L C M Yip, W C Vogt, S E Bohndiek and Members of IPASC (2022) Photoacoustics 26 100339.

The potential of photoacoustic imaging in radiation oncology.

Posted on March 27th, 2022, Published to

T L Lefebvre, E L Brown, L Hacker, T R Else, M Oraiopoulou, M R Tomaszewski, R Jena and S E Bohndiek (2022) Front Oncol. 12 803777.

Opti-MSFA: A toolbox for generalized design and optimization of multispectral filter arrays.

Posted on January 27th, 2022, Published to

T W Sawyer, M Taylor-Williams, R Tao, R Xia, C Williams and S E Bohndiek (2022) Opt Exp. 30 (5) 7591-7611.

2021

First-in-human pilot study of snapshot multispectral endoscopy for early detection of Barrett’s-related neoplasia.

Posted on September 27th, 2021, Published to

D J Waterhouse, S Bano, W Januszewicz, D Stoyanov, R C Fitzgerald, M di Pietro* and S E Bohndiek* (2021) J Biomed Opt. 26 (10) 106002.

A copolymer-in-oil tissue-mimicking material with tuneable acoustic and optical characteristics for photoacoustic imaging phantoms.

Posted on September 27th, 2021, Published to

L Hacker, J Joseph, A Ivory, M O Saed, B Zeqiri, S Rajagopal and S E Bohndiek (2021) IEEE Trans Med Imag. 40 (12) 3593-3603.

First experience in clinical application of hyperspectral endoscopy for evaluation of colonic polyps.

Posted on August 27th, 2021, Published to

J Yoon, J Joseph, D W Waterhouse, C Borzy, K Siemens, S Diamond, V L Tsikitis and S E Bohndiek (2021) J Biophot e202100078.

Technical and biological validation studies of a dual-wavelength LED-based photoacoustic and ultrasound imaging system.

Posted on July 27th, 2021, Published to

J Joseph, M K A Singh, N Sato and S E Bohndiek (2021) Photoacoustics 22 100267.

Spectral endoscopy enhances contrast for neoplasia in surveillance of Barrett’s esophagus.

Posted on June 27th, 2021, Published to

D J Waterhouse, W Januszewicz, S Ali, R C Fitzgerald, M di Pietro* and S E Bohndiek* (2021) Cancer Res 81 (12) 3415-3425.

Learned spectral decoloring enables photoacoustic oximetry

Posted on February 27th, 2021, Published to

J Gröhl, T Kirchner, T J Adler, L Hacker, N Holzwarth, A Hernández-Aguilera, M A Herrera, E Santos, S E Bohndiek, and L Maier-Hein (2021) Sci Rep 11 6565.

Multi-modal imaging of high-risk ductal carcinoma in situ of the breast using C2Am: a targeted cell death imaging agent.

Posted on January 27th, 2021, Published to

Z Szucs, J Joseph, T J Larkin, B Xie, S E Bohndiek, K M Brindle and A A Neves (2021) Breast Can Res 23 (1) 1-11.

2020

DNA-Based Nanocarriers to Enhance the Optoacoustic Contrast of Tumors In Vivo.

Posted on November 21st, 2020, Published to PubMed

J. Joseph, K. N. Baumann, A. Postigo, L. Bollepalli, S. E. Bohndiek and S. Hernández-Ainsa (2020) Adv Healthc Mater. Online ahead of print.

A Comparative Photophysical Study of Structural Modifications of Thioflavin T-Inspired Fluorophores

Posted on September 19th, 2020, Published to PubMed

L. M. Needham, J. Weber, C. M. Pearson, D. T. Do, F. Gorka, G. Lyu, S. E. Bohndiek, T. N. Snaddon and S. F. Lee (2020) J Phys Chem Lett. doi: 10.1021/acs.jpclett.0c01549.

Photoacoustics resolves species-specific differences in hemoglobin concentration and oxygenation

Posted on September 12th, 2020, Published to PubMed

L. Hacker, J. Brunker, E. St John Smith, I. Quiros-Gonzalez and S. E Bohndiek (2020) J Biomed Opt doi: 10.1117/1.JBO.25.9.095002.

A background correction method to compensate illumination variation in hyperspectral imaging

Posted on March 14th, 2020, Published to PubMed

J. Yoon, A. Grigoroiu and S. E. Bohndiek (2020) PLoS One. 15(3):e0229502. doi: 10.1371/journal.pone.0229502

Deep learning applied to hyperspectral endoscopy for online spectral classification

Posted on March 7th, 2020, Published to PubMed

A. Grigoroiu, J. Yoon and S. E. Bohndiek (2020) Sci Rep. 10(1):3947. doi: 10.1038/s41598-020-60574-6.

Co-registration of optoacoustic tomography and magnetic resonance imaging data from murine tumour models

Posted on February 15th, 2020, Published to PubMed

M Gehrung, M Tomaszewski, D McIntyre, J Disselhorst and S Bohndiek (2020) Photoacoustics 18:100147 doi: 10.1016/j.pacs.2019.100147

Twelve tips for engaging with biologists, as told by a physicist.

Posted on January 12th, 2020, Published to Nature

S E Bohndiek (2020) Nature 577(7789):283-284. doi: 10.1038/d41586-019-03961-y.

2019

Quantitative phase and polarization imaging through an optical fiber applied to detection of early esophageal tumorigenesis.

Posted on December 21st, 2019, Published to PubMed

G S D Gordon, J Joseph, M P Alcolea, T Sawyer, C Williams, C R M Fitzpatrick, P H Jones, M di Pietro, R C Fitzgerald, T D Wilkinson and S E Bohndiek (2019) J Biomed Opt. 24(12):1-13. doi: 10.1117/1.JBO.24.12.126004.

Grayscale-to-Color: Scalable Fabrication of Custom Multispectral Filter Arrays.

Posted on December 12th, 2019, Published to PubMed

C Williams, G S D Gordon, T D Wilkinson and S E Bohndiek (2019) ACS Photonics. 18;6(12):3132-3141. doi: 10.1021/acsphotonics.9b01196

Development of a blood oxygenation phantom for photoacoustic tomography combined with online pO2 detection and flow spectrometry.

Posted on October 19th, 2019, Published to PubMed

M Gehrung, S E Bohndiek and J Brunker (2019) J Biomed Opt. 24(12):1-11. doi: 10.1117/1.JBO.24.12.121908.

Full-field quantitative phase and polarisation-resolved imaging through an optical fibre bundle.

Posted on September 14th, 2019, Published to PubMed

G S D Gordon, J Joseph, T Sawyer, A J Macfaden, C Williams, T D Wilkinson and S E Bohndiek (2019) Opt Express. 27(17):23929-23947. doi: 10.1364/OE.27.023929.

An activatable cancer-targeted hydrogen peroxide probe for photoacoustic and fluorescence imaging.

Posted on August 31st, 2019, Published to PubMed

J Weber, L Bollepalli, A M Belenguer, M Di Antonio, N De Mitri, J Joseph, S Balasubramanian, C A Hunter and S E Bohndiek (2019) Cancer Res. [Epub ahead of print]

Photoacoustic imaging as a tool to probe the tumour microenvironment

Posted on July 28th, 2019, Published to PubMed

E Brown, J Brunker and S E Bohndiek (2019) Dis Model Mech. 12(7)

A roadmap for the clinical implementation of optical-imaging biomarkers

Posted on May 4th, 2019, Published to PubMed

D J Waterhouse, C R M Fitzpatrick, B W Pogue, J P B O'Connor and S E Bohndiek (2019) Nat Biomed Eng. 3: 339–353

A clinically translatable hyperspectral endoscopy (HySE) system for imaging the gastrointestinal tract

Posted on April 25th, 2019, Published to Nature Communications

J Yoon, J Joseph, D J Waterhouse, A S Luthman, G S D Gordon, M di Pietro, W Januszewicz, R C Fitzgerald and S E Bohndiek, Nature Communications, 10, Article number: 1902 (2019)

2018

Quantitative evaluation of comb-structure correction methods for multispectral fibrescopic imaging

Posted on December 12th, 2018, Published to PubMed

D J Waterhouse, A S Luthman, J Yoon, G S D Gordon and S E Bohndiek, Scientific Reports, 8, Article number: 17801 (2018).

Bimodal reflectance and fluorescence multispectral endoscopy based on spectrally resolving detector arrays

Posted on October 27th, 2018, Published to PubMed

A S Luthman, D J Waterhouse, L Ansel-Bollepalli, J Yoon, G S D Gordon, J Joseph, M di Pietro, W Januszewicz and S E Bohndiek (2018) J Biomed Opt. 24(3):1-14

Reconstruction of optical vector-fields with applications in endoscopic imaging

Posted on October 20th, 2018, Published to PubMed

M Gataric, G S D Gordon, F Renna, A G C P Ramos, M P Alcolea and S E Bohndiek (2019) IEEE Trans Med Imaging 38(4):955-967 doi: 10.1109/TMI.2018.2875875

An active DNA-based nanoprobe for photoacoustic pH imaging.

Posted on August 25th, 2018, Published to PubMed

K N Baumann, A C Fux, J Joseph, S E Bohndiek and S Hernández-Ainsa (2018) Epub ahead of print at Chem Commun (Camb)

Raman micro-spectroscopy for accurate identification of primary human bronchial epithelial cells.

Posted on August 25th, 2018, Published to PubMed

J M Surmacki, B J Woodhams, A Haslehurst, B A J Ponder and S E Bohndiek (2018) Sci Rep 8(1):12604

Oxygen-enhanced and dynamic contrast-enhanced optoacoustic tomography provide surrogate biomarkers of tumour vascular function, hypoxia and necrosis.

Posted on August 19th, 2018, Published to PubMed

M. R. Tomaszewski, M Gehrung, J Joseph, I Quiros Gonzalez, J A Disselhorst and S E Bohndiek, Cancer Res. 78(20):5980-5991 (2018).

Graphitic and oxidised high pressure high temperature (HPHT) nanodiamonds induce differential biological responses in breast cancer cell lines.

Posted on June 23rd, 2018, Published to PubMed

B Woodhams, L Ansel-Bollepalli, j Surmacki, H Knowles, L Maggini, M de Volder, M Atatüre and S E Bohndiek. (2018) Epub ahead of print at Nanoscale.

Optoacoustic Imaging Detects Hormone-Related Physiological Changes of Breast Parenchyma.

Posted on June 9th, 2018, Published to PubMed

O Abeyakoon, S Morscher, N Dalhaus, S J Ford, I A Mendichovszky, R Manavaki, M Wallis, P Moyle, R Woitek, A Patterson, T Torheim, J Joseph, I Q Gonzalez, S E Bohndiek, F J Gilbert. (2019) Ultraschall Med. 40(6)

Smart-Dust-Nanorice for Enhancement of Endogenous Raman Signal, Contrast in Photoacoustic Imaging, and T2-Shortening in Magnetic Resonance Imaging.

Posted on April 14th, 2018, Published to PubMed

C Pohling, J L Campbell, T A Larson, D Van de Sompel, J Levi, M H Bachmann, S E Bohndiek, J V Jokerst and S S Gambhir, Small. 14(19):e1703683 (2018)

Emerging optical methods for endoscopic surveillance of Barrett’s oesophagus.

Posted on April 14th, 2018, Published to PubMed

D J Waterhouse, C R M Fitzpatrick, M di Pietro and S E Bohndiek. (2018) Lancet Gastroenterol Hepatol. 3(5):349-362

Optoacoustics delineates murine breast cancer modelsdisplaying angiogenesis and vascular mimicry

Posted on March 28th, 2018, Published to PubMed

I Quiros-Gonzalez, M Tomaszewski, S Aitken, L Ansel-Bollepalli, L McDuffus, M Gill, L Hacker, J Brunker and S E Bohndiek (2018) ePub ahead of print at Br J Cancer

Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species.

Posted on March 11th, 2018, Published to PubMed

L M Needham, J Weber, J W B Fyfe, O M Kabia, D T Do, E Klimont, Y Zhang, M Rodrigues, C M Dobson, S Ghandi, S E Bohndiek, T N Snaddon, S F Lee. (2018) R Soc Open Sci. 5(2):171399

Processing methods for photoacoustic Doppler flowmetry with a clinical ultrasound scanner

Posted on February 27th, 2018, Published to PubMed

Thore M. Bücking; Pim J. van den Berg; Stavroula Balabani; Wiendelt Steenbergen; Paul C. Beard; Joanna Brunker

Detection of early neoplasia in Barrett’s esophagus using lectin-based near-infrared imaging: an ex vivo study on human tissue.

Posted on January 21st, 2018, Published to PubMed

A A Neves, M Di Pietro, M O'Donovan, D J Waterhouse, S E Bohndiek, K M Brindle and R C Fitzgerald. (2018) Endoscopy. Jun;50(6):618-625. doi: 10.1055/s-0043-124080.

2017

Distance dependent photoacoustics revealed through DNA nanostructures.

Posted on October 21st, 2017, Published to PubMed

J Joseph, K N Baumann, P Koehler, T J Zuehlsdorff, D J Cole, J Weber, S E Bohndiek and S Hernández-Ainsa. (2017) Nanoscale. Nov 2;9(42):16193-16199.

Optoacoustic detection of early therapy-induced tumor cell death using a targeted imaging agent.

Posted on October 14th, 2017, Published to PubMed

B Xie, M R Tomaszewski, A Neves, S Ros, D Hu, S McGuire, S Mullins, D A Tice, R C A Sainson, S E Bohndiek, R W Wilkinson and K M Brindle. (2017) ePub ahead of print at Clin Cancer Res.

Current and Emerging Technologies for Probing Molecular Signatures of Traumatic Brain Injury.

Posted on October 14th, 2017, Published to PubMed

A Ercole, S Magnoni, G Vegliante, R Pastorelli, J Surmacki, S E Bohndiek and E R Zanier. (2017) Frontiers Neurology 8 (AUG) 450.

Photoacoustic imaging using genetically encoded reporters: a review.

Posted on October 14th, 2017, Published to PubMed

J Brunker, J J Yao, J Laufer and S E Bohndiek. (2017) J. Biomed. Opt. 22 (7) 070901.

Oxygen enhanced photoacoustic imaging reveals vascular dynamics in murine models of prostate cancer.

Posted on October 14th, 2017, Published to PubMed

M R Tomaszewski, I Quiros-Gonzalez, J O'Connor, O Abeyakoon, G Parker, K Williams, F Gilbert and S E Bohndiek (2017) Theranostics. 7 (11) 2900-2915.

Wide field fluorescence hyperspectral imaging (fHSI) for biomedical applications.

Posted on May 12th, 2017, Published to PubMed

A S N Luthman, S Dumitru, I Quiros-Gonzalez, J Joseph and S E Bohndiek. (2017) J. Biophotonics. 10 (6-7) 840-853.

Tolerancing the alignment of large core optical fibers, fiber bundles and light guides using a Fourier approach.

Posted on May 12th, 2017, Published to PubMed

T W Sawyer, R Petersberg and S E Bohndiek (2017) Appl Opt. 56 (12) 3303-3310.

Assessing oxidative stress in tumors by measuring the rate of hyperpolarized [1-13C]dehydroascorbic acid reduction using 13C magnetic resonance spectroscopy.

Posted on May 12th, 2017, Published to PubMed

K N Timm, D Hu, M Williams, A J Wright, M I Kettunen, B W Kennedy, T J Larkin, F Bulat, P Dzien, I Marco-Rius, S E Bohndiek and K M Brindle (2017) J Biol Chem. 292 (5) 1737-1748.

Imaging biomarker roadmap for cancer studies.

Posted on May 12th, 2017, Published to PubMed

J P B O’Connor, …, S E Bohndiek et al (2017) Nature Reviews Clin Onc. 14 (3) 169-186.

Evaluation of illumination system uniformity for wide-field biomedical hyperspectral imaging.

Posted on March 1st, 2017, Published to IoP

T W Sawyer, A S N Luthman and S E Bohndiek (2017). J Opt. 19 045301.

Evaluation of precision of optoacoustic tomography for preclinical imaging of living subjects.

Posted on March 1st, 2017, Published to PubMed

J Joseph, M R Tomaszewski, I Quiros Gonzalez, J Weber, J Brunker and S E Bohndiek. (2017) J Nucl Med. 58 807-814.

Label-free monitoring of tissue biochemistry following traumatic brain injury using Raman spectroscopy.

Posted on March 1st, 2017, Published to PubMed

J M Surmacki, L Bollepalli, F Pischiutta, E R Zanier, A Ercole and S E Bohndiek. (2017) Analyst. 142 132-139.

2016

Towards Quantitative Evaluation of Tissue Absorption Coefficients Using Light Fluence Correction in Optoacoustic Tomography

Posted on September 20th, 2016, Published to PubMed

F M Brochu, J Brunker, J Joseph, M R Tomaszewski, S Morscher and S E Bohndiek (2017) IEEE Trans Med Imag 36 (1) 332-331.

Design and validation of a near-infrared fluorescence endoscope for detection of early esophageal malignancy

Posted on August 10th, 2016, Published to PubMed

D J Waterhouse, J Joseph, A A Neves, M di Pietro, K M Brindle, R C Fitzgerald and S E Bohndiek (2016) J. Biomed. Opt. 21(8), 084001.

Contrast Agents for Molecular Photoacoustic Imaging

Posted on August 2nd, 2016, Published to PubMed

J Weber, P C Beard and S E Bohndiek (2016) Nat Meth 13(8):639-50

2015

Single-pixel phase-corrected fiber bundle endomicroscopy with lensless focussing capability.

Posted on September 25th, 2015, Published to IEEExplore

G S D Gordon, J Joseph, S E Bohndiek and T D Wilkinson (2015) J Lightwave Technol. 33 16 3419-3425.

Photoacoustic tomography detects early vessel regression and normalization during ovarian tumor response to the anti-angiogenic therapy Trebananib.

Posted on September 25th, 2015, Published to PubMed

S E Bohndiek, Laura S Sasportas, Steve Machtaler, Jesse V Jokerst, Sharon Hori and Sanjiv S Gambhir (2015) J Nucl Med. Accepted.

2014

Active Pixel CMOS-Based Radiation Detectors

Posted on September 25th, 2014, Published to ScienceDirect

C Arvanitis and S E Bohndiek (2014) ‘Chapter 618: Active Pixel CMOS-Based Radiation Detectors’ in Comprehensive Biomedical Physics (Elsevier)

Analysis of image heterogeneity using 2D Minkowski functionals detects tumor responses to treatment.

Posted on September 25th, 2014, Published to PubMed

T Larkin, H Canuto, M Kettunen, T Booth, D Hu, A S Krishnan, S E Bohndiek, A A Neves, C McLachlan, M P Hobson and K M Brindle (2014) Magn Reson Med 71 (1) 402-410.

Quantitation of a spin polarization-induced nuclear Overhauser effect (SPINOE) between a hyperpolarized 13C-labeled cell metabolite and water protons.

Posted on September 25th, 2014, Published to PubMed

I Marco-Ruis, S E Bohndiek, M I Kettunen, T J Larkin, M Basharat, C Seeley and K M Brindle (2014) Contrast Media Mol Imaging 9 (2) 182-186.

Cellulose nanoparticles are a biodegradable photoacoustic contrast agent in living mice.

Posted on September 25th, 2014, Published to ScienceDirect

J V Jokerst, D Van de Sompel, S E Bohndiek, and S S Gambhir (2014) Photoacoustics. 2 3 119-127.

2013

Molecular imaging with gold nanoparticles combined with Surface Enhanced Raman Spectroscopy

Posted on September 25th, 2013, Published to FutureMedicine

S E Bohndiek and S S Gambhir (2013) Imaging Med 5 (1) 11-14.

Molecular photoacoustic imaging of follicular thyroid carcinoma.

Posted on September 25th, 2013, Published to PubMed

J Levi, S R Kothapalli, S E Bohndiek, J K Yoon, A Dragulescu-Andrasi, C Nielsen, A Tisma, S Bodapati, G Gowrishankar, X Yan, C T Chan, D Starcevic and S S Gambhir (2013) Clin Cancer Res 19 (6) 1-9.

Development and application of stable phantoms for the evaluation of photoacoustic imaging instruments.

Posted on September 25th, 2013, Published to PubMed

S E Bohndiek, S Bodapati, D Van De Sompel, S R Kothapalli and S S Gambhir (2013) PLoS One 8 (9) e75533.

A small animal Raman instrument for rapid, wide-area, spectroscopic imaging

Posted on August 20th, 2013, Published to PubMed

S E Bohndiek, A Wagadarikar, C L Zavaleta, D Van De Sompel, E Garai, J V Jokerst, S Yazdanfar and S S Gambhir (2013) Proc Natl Acad Sci USA 110 (30) 12408-12413

2012

Hyperpolarized 13C spectroscopy detects early changes in tumor vasculature and metabolism after VEGF neutralization.

Posted on September 25th, 2012, Published to PubMed

S E Bohndiek, M I Kettunen, D Hu and K M Brindle (2012) Cancer Res 72 854-864.

Magnetic resonance imaging with hyperpolarized [1, 4-13C2] fumarate allows detection of early renal acute tubular necrosis.

Posted on September 25th, 2012, Published to PubMed

M R Clatworthy, M I Kettunen, D Hu, R J Mathews, T H Witney, B W C Kennedy, S E Bohndiek, F A Gallagher, L B Jarvis, K G C Smith and K M Brindle (2012) Proc Natl Acad Sci USA 109 (33) 13374-13379.

Improving image quality by accounting for changes in water temperature during a photoacoustic tomography scan.

Posted on September 25th, 2012, Published to PubMed

D Van de Sompel, L S Sasportas, A Dragulescu-Andrasi, S E Bohndiek and S S Gambhir (2012) PLoS ONE 7 (10) e45337.

2011

Tumor imaging using hyperpolarized 13C magnetic resonance spectroscopy.

Posted on September 25th, 2011, Published to PubMed

K M Brindle, S E Bohndiek, F A Gallagher and M I Kettunen (2011) Magn Reson Med 66 (2) 505-19.

Hyperpolarized 13C MRS and PET: complementary techniques for investigating tumor biochemistry in vivo.

Posted on September 25th, 2011, Published to PubMed

F A Gallagher, S E Bohndiek, M I Kettunen, D Y Lewis, D Soloviev and K M Brindle (2011) J Nucl Med 52 (9) 1333-1336.

Hyperpolarized [1-13C]-Ascorbic and Dehydroascorbic Acid: Vitamin C as a probe for imaging redox status in vivo

Posted on August 25th, 2011, Published to PubMed

S E Bohndiek, M I Kettunen, D Hu, B W C Kennedy, J Boren, F A Gallagher and K M Brindle (2011) J Am Chem Soc A 133 (30) 11795-11801.

2010

Magnetization Transfer Measurements of Exchange between Hyperpolarized [1-13C]-pyruvate and [1-13C]-lactate in a murine lymphoma.

Posted on September 25th, 2010, Published to PubMed

M I Kettunen, D Hu, T H Witney, R McLaughlin, F A Gallagher, S E Bohndiek, S E Day and K M Brindle (2010) Magn Reson Med 63 (4) 872-880.

Optical characterisation of a CMOS active pixel sensor using periodic noise reduction techniques.

Posted on September 25th, 2010, Published to ScienceDirect

A C Konstantinidis, A Olivo, P Munro, S E Bohndiek and R Speller (2010) Nucl Inst Meth A 620 (2-3) 549-556.

Characterisation of regional variations in a stitched CMOS active pixel sensor.

Posted on September 25th, 2010, Published to ScienceDirect

H M Zin, A C Konstantinidis, E J Harris, J F P Osmond, A Olivo, S E Bohndiek, A T Clark et al (2010) Nucl Inst Meth A 620 (2-3) 540-548.

Imaging and ‘omic’ methods in the molecular diagnosis of cancer.

Posted on September 25th, 2010, Published to PubMed

S E Bohndiek and K M Brindle (2010) Expert Rev Mol Diagn 10 (4) 417-434.

Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarized [1-13C]pyruvate and [1,4-13C2]fumarate

Posted on September 25th, 2010, Published to PubMed

T H Witney, M I Kettunen, D Hu, F A Gallagher, S E Bohndiek, R Napolitano and K M Brindle (2010) Br J Cancer 103 (9) 1400-1406.

Detecting tumor response to a vascular disrupting agent using 13C magnetic resonance spectroscopy and hyperpolarized [1-13C]pyruvate and [1,4-13C2]fumarate.

Posted on September 25th, 2010, Published to PubMed

S E Bohndiek, M I Kettunen, D Hu, T H Witney, B W C Kennedy, F A Gallagher and K M Brindle (2010) Mol Cancer Ther 9 (12) 3278 – 3288.

2009

Signal and noise transfer of a CMOS based active pixel flat panel imager coupled to structured CsI:Tl.

Posted on September 25th, 2009, Published to PubMed

C D Arvanitis, S E Bohndiek, J Blakesley, A Olivo and R D Speller (2009) Med Phys 36 116-126.

A CMOS Image Sensor with In-Pixel ADC, Timestamp and Sparse Readout.

Posted on September 25th, 2009, Published to IEEExplore

J P Crooks, S E Bohndiek, H XingLiang, B Ott, J Osmond, G Villani, A Clark, R Halsall, M et al (2009) IEEE Sensors 9 20-28.

A non-free-space propagation x-ray phase contrast imaging method sensitive to phase effects in two directions simultaneously.

Posted on September 25th, 2009, Published to AIP

A Olivo, S E Bohndiek, J Griffiths, A Konstantinidis and R D Speller (2009) Appl Phys Lett 94 044108.

An Active Pixel Sensor-based X-ray diffraction system for breast biopsy analysis.

Posted on September 25th, 2009, Published to PubMed

S E Bohndiek, G J Royle and R D Speller (2009) Phys Med Biol 54 3513-3527.

The Multidimensional Integrated Intelligent Imaging project (MI-3).

Posted on September 25th, 2009, Published to PubMed

N Allinson, T Anaxagoras, J Aveyard, C Arvanitis, R Bates, A Blue, S E Bohndiek, J Cabello et al (2009) Nucl Inst Meth A 604 196-198.

Characterization and testing of LAS: a prototype ‘Large Area Sensor’ with performance characteristics suitable for medical imaging applications. I

Posted on September 25th, 2009, Published to IEEExplore

S E Bohndiek, A Blue, J Cabello, A T Clark, N Guerrini, P M Evans, E J Harris, A Konstantinidis, et al (2009) EEE Trans Nucl Sci 56 (5) 2938-2946.

Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.

Posted on September 25th, 2009, Published to PubMed

F A Gallagher, M I Kettunen, D Hu, P R Jensen, R in't Zandt, M Karlsson, A Gisselsson,... S E Bohndiek, et al (2009) Proc Natl Acad Sci USA 106 (47) 19801-19806.

2008

A CMOS Active Pixel Sensor system for laboratory-based x-ray diffraction of biological tissue.

Posted on September 25th, 2008, Published to PubMed

S E Bohndiek, E J Cook, C D Arvanitis, A Olivo, G J Royle, A T Clark, M L Prydderch, R Turchetta and R D Speller (2008) Phys Med Biol 53 655-672.

Comparison of methods for estimating the conversion gain of CMOS Active Pixel Sensors.

Posted on September 25th, 2008, Published to IEEExplore

S E Bohndiek, A Blue, A T Clark, M L Prydderch, R Turchetta, G J Royle and R D Speller (2008) IEEE Sensors 10 1734-1744.

2007

Characterisation of Vanilla – A novel active pixel sensor for radiation detection.

Posted on September 25th, 2007, Published to ScienceDirect

A Blue, R Bates, A Laing, D Maneuski, V O’Shea, A Clark, S E Bohndiek et al (2007) Nucl Inst Meth A 591 287-290.

Correlation of energy dispersive diffraction signatures and microCT of small breast tissue samples with pathological analysis.

Posted on September 25th, 2007, Published to PubMed

J A Griffiths, G J Royle, A M Hanby, J A Horrocks, S E Bohndiek and R D Speller (2007) Phys Med Biol 52 6151-6164.

First evidence of phase-contrast imaging with laboratory sources and active pixel sensors.

Posted on September 25th, 2007, Published to ScienceDirect

A Olivo, C D Arvanitis, S E Bohndiek, A T Clark, M Prydderch, R Turchetta and R D Speller (2007) Nucl Inst Meth A 581 776-782.

Empirical electro-optical and x-ray performance evaluation of CMOS Active Pixel Sensors for low dose, high resolution x-ray medical imaging.

Posted on September 25th, 2007, Published to PubMed

C D Arvanitis, S E Bohndiek, G J Royle, A Blue, H X Liang, A Clark, M Prydderch, R Turchetta, R D Speller (2007) Med Phys 34 4612-4625.

Characterization studies of two novel Active Pixel Sensors.

Posted on September 25th, 2007, Published to SPIE

S E Bohndiek, C D Arvanitis, G J Royle, A T Clark, J P Crooks, M L Prydderch, R Turchetta, A Blue, V O’Shea and R D Speller (2007) Opt Eng 46 124003.